Growth hormone is DNA recombinant human growth hormone, which has the same function as human growth hormone. It can promote the growth of bone, viscera and whole body, promote the synthesis of protein, affect the metabolism of fat and minerals, and play a key role in human growth and development. Subcutaneous injection of about 80% was absorbed, 5 hours to reach the peak of blood drug concentration, the half-life of 4 hours. About 90% of the injection dose is metabolized in the liver. Only about 0.1% of the dose is excreted from the biliary tract and the kidneys.
Research course:
1. Scientists knew the existence of growth hormone as early as 1920, and began to use animal growth hormone, but later proved its inactivity to humans.
2. Growth hormone was successfully extracted from human pituitary gland in 1957, but it was found to cause Creutzfeldt-Jakob disease and death, so the drug is no longer used.
3. In the late 1970s, recombinant DNA technology was used to obtain human growth hormone gene, which was introduced into eukaryotic cells. These cells could produce a large amount of growth hormone after obtaining the information of hGH synthesis.
4. hGH produced by early genetic engineering has 192 amino acid residues. It has one more methionine at the N-terminal of normal growth hormone molecule. It is effective in the treatment of growth hormone deficiency, but it is easy to produce antibodies and affect the curative effect.
5. By removing methionine, purifying and applying the new recombinant DNA technology of mammalian cells, the purity of growth hormone has been greatly improved.
Koffeepharm Co.,Ltd has been established since 2003, and specialized in HGH & Peptide and Steroid formore than 15 years.All products are manufactured by GMP factory. What’s more, Koffeepharm is familiar with the quality & testing issue of their market. Every batch of hgh will be tested before shipment.
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