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Agomelatine
- Product description: supply good quality Agomelatine CAS:138112-76-2
PRODUCT INTRODUCTION
Agomelatine
Detailed Product Description
|
CAS: |
138112-76-2 |
Appreance: |
White Powder. |
Minimum Order Quantity: |
10 Grams. |
Usage: |
Fat Loss |
|
Standard: |
USP28/BP2003 |
Purity: |
99.85% By HPLC. |
|
Grade: |
Pharma Grade |
Nootropic Sleep Aid Agomelatine Melatonergic Antidepressant CAS 138112-76-2
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Product Name:AGOMELATINE
Synonyms:AGOMELATINE;n-(2-(7-methoxy-1-naphthalenyl)ethyl)-acetamid;n-(2-(7-methoxy-1-naphthalenyl)ethyl)acetamide;n-(2-(7-methoxynaphth-1-yl)ethyl)acetamide;S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide;S 20098;AGOMELATIN;Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-
CAS:138112-76-2
MF:C15H17NO2
MW:243.30098
Product Categories: Aromatics Compounds;Aromatics;Neurochemicals;APIS;API;Agomelatine;Valdoxan, Melitor, Thymanax
ApplicationMelatonin drugs.
Chemical Properties:White Solid
Usage: Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of
Usage: Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.
What is Agomelatine?
Agomelatine (BAN, rINN; trade names Valdoxan, Melitor, Thymanax) is a melatonergic antidepressant developed by the pharmaceutical company Servier. Agomelatine is marketed for the treatment of major depressive disorder, primarily for its relatively favorable side effect profile: it avoids the weight gain, sexual dysfunction, and severe withdrawal associated with the most commonly used classes of antidepressants (SSRIs, SNRIs, tricyclics), while providing similar therapeutic benefit.
Due to its distinctive mechanism of action, agomelatine is also studied for its effects on sleep regulation. Studies report various improvements in general quality of sleep metrics, as well as specific therapeutic benefits in circadian rhythm disorders.
How does it work?
Valdoxan tablets contain the active ingredient agomelatine, which is a type of medicine called an antidepressant. It is used to treat depression.
Agomelatine acts on the melatonin and serotonin receptors in the brain.
Melatonin is a hormone made by the pineal gland, a structure in the brain. It is normally released soon after it starts to get dark. The amount produced then increases until about four am, before dropping off again. Melatonin is linked with the control of circadian rhythms and promoting sleep. It works by acting on melatonin receptors in the brain.
Agomelatine mimics the action of melatonin and helps to re-synchronise the body's circadian rhythms. These include mood, anxiety, appetite, body temperature and sleep/wake cycles. These circadian rhythms, particularly sleep cycles, are severely disturbed in people with depression. Agomelatine's main action is to improve the onset and quality of sleep and this in turn has an antidepressant effect.
Agomelatine also helps to improve mood in depression by increasing noradrenaline and dopamine release in the brain. These are natural chemicals called neurotransmitters that are involved, amongst other things, in regulating mood.
Before taking agomelatine:
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking agomelatine it is important that your doctor knows:
If you are under 18 or over 75 years of age.
If you are pregnant or breast-feeding.
If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.
If you have ever had abnormally 'high' moods or dementia.
If you are taking any other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to a medicine.
Our advantages:
Over 15years specialized in this field,Professional & Experienced sevices provided.
1. Best prices with High quality.We have complete QA&QC system;steroid powder purity is more than 99% hplc. We use the right recipe to cook the injectable steroid oil. All our order will send out after passing the test exam.
2. Rich experienced in delivering the parcels to you.The most disguise package and the most professional shipping company to ensure safe delivery. .
3. Enough stock ensure the prompt delivery time.
4. Good after-sales service.
5. Specials are possible when the order is big enough.
6. The most important thing is that we have resend policy to protect you 100%.
Packaging & Delivery:
We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.
Payment & Shipping Terms:
Minimum Order Quantity:10g
Price:Negotiable
Packing:safety & discreet pkg or as required
Delivery Time: within 24hours after receiving full payment.
Payment terms:T/T,Western Union,MoneyGram.
Supply ability:200kg/month
How to proceed an order:
1st: Please let me know what you need-Which product/Cas No. quantity, and the destination country.
2nd: You send us the purchase order once we cme to an agreement on all details.
3rd: Parcel would be delivered upon full payment received.
4th: Express Tracking No.will be provided about the parcels.
5th: You will get the parcels in 7days.
6th: After-sales service would be provided after you receive parcels.
Should you have any inquires please feel free to contact me ,sophia@koffeepharm.com.