Emoxypine Succinate

Emoxypine Succinate is an inhibitor of free-radical processes, membrane protectors. Has antihypoxia, antistress, nootropic, anticonvulsant and anxiolytic effects. The drug increases the body’s resistance to a variety of damaging factors (shock, hypoxia and ischemia, cerebrovascular accident, alcohol intoxication and antipsychotics/neuroleptics).

The mechanism of action Emoxypine Succinate due to its antioxidant, anti-hypoxic and membrane-protektive action. The drug inhibits lipid peroxidation, increases the activity of superoxide dismutase, increases the ratio of lipid-protein membrane reduces the viscosity and increases its fluidity. Emoxypine Succinate modulates the activity of membrane enzymes (calcium-independent phosphodiesterase, adenylate cyclase, acetylcholinesterase) receptor complexes (benzodiazepine, GABA, acetylcholine) that enhances their ability to bind to ligands, contributes to maintaining the structural and functional organization of biological membranes, transport of neurotransmitters and improve synaptic transmission. Emoxypine Succinate increases in the brain dopamine. Causes an increase in compensatory activation of aerobic glycolysis and decreased inhibition of oxidative processes in the Krebs cycle under hypoxic conditions with an increase in ATP and creatine phosphate, activation energy-synthesis mitochondrial function, stabilization of cell membranes.

The drug improves metabolism and blood circulation of the brain, improves microcirculation and blood rheology, reduces platelet aggregation. Stabilizes the membrane structure of red blood cells (erythrocytes and platelets) during hemolysis. Has hypolipidemic effect, reduces total cholesterol and LDL.

Anti-stress effect is to normalize post-stress behavior, somatic-vegetative disorders, recovery cycles “sleep-wake” disturbed learning and memory processes, and reducing the degenerative morphological changes in different brain structures.

Emoxypine Succinate has a strong antitoxic action with withdrawal syndrome. Eliminates neurological and neurotoxic manifestations of acute alcohol intoxication, restores behavioral disorders, autonomic functions, and is also capable of shooting cognitive impairment caused by long-term administration of ethanol and its abolition. Influenced Emoxypine Succinate amplifies the tranquilizing effect, antipsychotic, antidepressant, hypnotics, and anticonvulsants, which allows them to reduce the dose and reduce side effects.

Emoxypine Succinate improves the functional state of the ischemic myocardium. In the context of coronary heart disease increases collateral blood flow to ischemic myocardium, helps to preserve the integrity of cardiomyocytes and maintain their functional activity. Effectively restores myocardial contractility in a reversible cardiac dysfunction.